Neurological sequelae of intrauterine warfarin exposure

J Clin Neurosci. 2007 Feb;14(2):99-103. doi: 10.1016/j.jocn.2006.03.031. Epub 2006 Nov 14.

Abstract

Warfarin embryopathy is a well-defined manifestation of intrauterine warfarin exposure. The embryopathy phenotype as it relates to the nervous system is broad and poorly recognised. We describe an adult with neurological sequelae of fetal warfarin exposure. We review previous cases with neurological sequelae and discuss the pathogenetic mechanism in light of recent research.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Abnormalities, Drug-Induced / etiology*
  • Adult
  • Anticoagulants / adverse effects*
  • Cognition Disorders / chemically induced
  • Deafness / chemically induced*
  • Humans
  • Male
  • Nasal Bone / abnormalities*
  • Spinal Cord Diseases / chemically induced*
  • Spine / abnormalities
  • Warfarin / adverse effects*

Substances

  • Anticoagulants
  • Warfarin