Transfusion requirements during liver transplantation: impact of a temporary portacaval shunt

Transplant Proc. 2006 Oct;38(8):2486-7. doi: 10.1016/j.transproceed.2006.08.045.

Abstract

We evaluated the consumption of blood products during liver transplantation in cirrhotic patients association with the placement of a temporary portacaval shunt (TPCS).

Patients and methods: We retrospectively divided 349 cirrhotic patients transplanted in our unit between March 1997 and October 2005 into two groups: transplants without a TPCS (group I, 189 cases) and those with a TPCS (group II, 160 cases). In all cases, we preserved the inferior vena cava (piggyback). The dependent variables were consumption of blood-derived products (banked red cells, recovered red cells, fresh frozen plasma, platelets), surgery time, kidney function, intensive care unit stay, and hospital stay.

Results: Consumption of blood products was significantly lower among patients who received a TPCS. In group II, no platelet transfusion was required in 54% of the patients, and no banked red cells in 12% compared with 18% and 3%, respectively, among group I patients (P < .005). The mean overall transplant procedure time was 74 minutes shorter in group II (361 minutes) compared with group I (435 minutes) (P < .001). The overall hospital stay was shorter among patients transplanted after TPCS.

Conclusion: Liver transplantation with a TPCS was accompanied by a reduction in the intraoperative use of blood-derived products, especially platelet transfusion. Among other advantages, this reduction resulted in a shorter posttransplant hospital stay.

MeSH terms

  • Blood Component Transfusion*
  • Blood Loss, Surgical
  • Blood Transfusion*
  • Humans
  • Intraoperative Care*
  • Liver Cirrhosis / surgery
  • Liver Transplantation / physiology*
  • Portacaval Shunt, Surgical*
  • Retrospective Studies