Evaluation of commercial rubella immunoglobulin G avidity assays

J Clin Microbiol. 2007 Jan;45(1):231-3. doi: 10.1128/JCM.01243-06. Epub 2006 Nov 8.

Abstract

We compared the performances of five commercial rubella virus immunoglobulin G (IgG) avidity assays. The Adaltis (kappa = 0.28) and Diesse (kappa = 0.33) assays showed poor correlation, the Behring assay (kappa = 0.68) showed good correlation, and the Euroimmun (kappa = 0.95) and Radim (kappa = 0.94) assays showed excellent correlation with a well-established in-house rubella virus IgG avidity assay. The Euroimmun and Radim assays were statistically significantly better than the other commercial assays (P < 0.01).

Publication types

  • Evaluation Study

MeSH terms

  • Antibodies, Viral / blood
  • Antibodies, Viral / immunology
  • Antibody Affinity*
  • Female
  • Humans
  • Immunoglobulin G / blood*
  • Immunoglobulin G / immunology
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / immunology*
  • Reagent Kits, Diagnostic*
  • Rubella / diagnosis
  • Rubella / immunology*
  • Rubella virus / immunology

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Reagent Kits, Diagnostic