Mifepristone-induced abortion in one horn and a growing fetus in another horn in a patient with a twin pregnancy in a bicornuate uterus

Fertil Steril. 2006 Dec;86(6):1764.e3-5. doi: 10.1016/j.fertnstert.2006.03.072. Epub 2006 Nov 1.

Abstract

Objective: To report a case of mifepristone-induced abortion in only one horn but a growing fetus in another horn for a twin pregnancy in a bicornuate uterus.

Design: Case report.

Setting: Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Taiwan.

Patient(s): A 31-year-old woman who conceived spontaneously presented with 37 days' gestation.

Intervention(s): Mifepristone 600 mg orally followed by misoprostol 400 mug orally 2 days later.

Main outcome measure(s): Termination of pregnancy.

Result(s): Induced abortion in only one horn but a growing fetus in another horn for a twin pregnancy in the bicornuate uterus detected by ultrasound. Surgical abortion with vacuum curettage was performed, and menstruation resumed 1 month later.

Conclusion(s): As medical abortion with mifepristone and misoprostol becomes more prevalent, more studies are necessary to establish the dosage and regimens for multiple pregnancies associated with uterine anomalies.

Publication types

  • Case Reports

MeSH terms

  • Abortion, Induced*
  • Adult
  • Female
  • Humans
  • Mifepristone*
  • Pregnancy
  • Pregnancy, Multiple / drug effects*
  • Treatment Outcome
  • Twins*
  • Uterus / abnormalities*
  • Uterus / drug effects*
  • Vacuum Curettage

Substances

  • Mifepristone