A facile and clean direct cyanation of heteroaromatic compounds using a recyclable hypervalent iodine(III) reagent

Toshifumi Dohi; Koji Morimoto; Naoko Takenaga; Akinobu Maruyama; Yasuyuki Kita

doi:10.1248/cpb.54.1608

A facile and clean direct cyanation of heteroaromatic compounds using a recyclable hypervalent iodine(III) reagent

Chem Pharm Bull (Tokyo). 2006 Nov;54(11):1608-10. doi: 10.1248/cpb.54.1608.

Authors

Toshifumi Dohi¹, Koji Morimoto, Naoko Takenaga, Akinobu Maruyama, Yasuyuki Kita

Affiliation

¹ Graduate School of Pharmaceutical Sciences, Osaka University, Suita, Osaka, Japan.

PMID: 17077564
DOI: 10.1248/cpb.54.1608

Abstract

The facile and clean direct cyanating reaction of pyrroles and thiophenes has been achieved using a recyclable hypervalent iodine(III) reagent 1b by a simple solid-liquid separation of the products and the reagent.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cyanates / chemistry*
Heterocyclic Compounds / chemical synthesis*
Heterocyclic Compounds / chemistry
Hydrocarbons, Aromatic / chemical synthesis*
Hydrocarbons, Aromatic / chemistry
Hydrocarbons, Iodinated / chemistry*
Molecular Structure
Oxidation-Reduction
Stereoisomerism

Substances

Cyanates
Heterocyclic Compounds
Hydrocarbons, Aromatic
Hydrocarbons, Iodinated