New sesquiterpene lactones from the aerial parts of Pseudoelephantopus spicatus

Chem Pharm Bull (Tokyo). 2006 Nov;54(11):1599-601. doi: 10.1248/cpb.54.1599.

Abstract

Two new sesquiterpene lactones, spicatolide C (1) and spicatocadinanolide A (2), have been isolated along with the known piptocarphol isomers (3, 4) and one eudismane type sesquiterpene (5) from the EtOAc extract of the aerial parts of Pseudoelephantopus spicatus. The structures and the relative stereochemistries of the new metabolites were determined by spectroscopic methods.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Asteraceae / chemistry*
  • Lactones / chemistry*
  • Lactones / isolation & purification
  • Magnetic Resonance Spectroscopy / methods
  • Magnetic Resonance Spectroscopy / standards
  • Models, Molecular
  • Molecular Conformation
  • Plant Components, Aerial / chemistry*
  • Plants, Medicinal / chemistry*
  • Reference Standards
  • Sesquiterpenes / chemistry*
  • Sesquiterpenes / isolation & purification
  • Stereoisomerism

Substances

  • Lactones
  • Sesquiterpenes
  • spicatocadinanolide A
  • spicatolide C