Nasal sound analysis: a new method for evaluating nasal obstruction in allergic rhinitis

Laryngoscope. 2006 Nov;116(11):2050-4. doi: 10.1097/01.mlg.0000240173.74885.0d.

Abstract

Objective: Current measurements of nasal obstruction are unreliable and may be improved with the development of new techniques. The effectiveness of odiosoft-rhino (OR) in the evaluation of nasal obstruction was investigated in a blind comparison at a referral center, institutional practice.

Patients: Forty-eight patients with perennial allergic rhinitis and 52 healthy subjects were studied. Nasal endoscopic examination, acoustic rhinometry (AR), and OR were performed and symptom scores compared.

Main outcome measure: Assessment of nasal blockage with OR method was the main outcome measure.

Results: Using the OR technique, significant differences were observed between the patient and control groups. OR data correlated with symptom scores and endoscopic examination. However, this was not observed with AR. A 15.5-dB cutoff point for the left side and 14.5 dB cutoff point for the right side at the 2,000 to 4,000 Hz frequency interval resulted in 93.8% sensitivity and 92.3% specificity and 72.9% sensitivity and 80.8% specificity, respectively. A 8.5-dB cutoff point for the left and right sides at the 4,000 to 6,000 Hz frequency interval resulted in 87.5% sensitivity and 80.8% specificity and 70.8% sensitivity and 78.8% specificity, respectively.

Conclusion: OR is a simple, noninvasive test for assessing nasal obstruction. The OR technique can detect nasal obstruction with high sensitivity and specificity, and these findings correlate with symptoms and physical examination.

MeSH terms

  • Adult
  • Female
  • Humans
  • Hypertrophy
  • Male
  • Middle Aged
  • Pain Measurement
  • Peptide Hydrolases
  • ROC Curve
  • Rhinitis, Allergic, Perennial / complications*
  • Rhinometry, Acoustic
  • Sensitivity and Specificity
  • Signal Processing, Computer-Assisted
  • Turbinates / pathology

Substances

  • opacity factor
  • Peptide Hydrolases