Hepatitis C virus genotype 4 in Ugandan children and their mothers

Emerg Infect Dis. 2006 Sep;12(9):1440-3. doi: 10.3201/eid1209.041068.

Abstract

In Kampala, Uganda, in 2001, hepatitis C virus antibodies were found in 27 (4%) of 603 children and in 62 (12%) of 525 of their mothers. However, only approximately 10% of positive results were confirmed by reverse transcription-PCR, which suggests frequent false-positive results or viral clearance. All sequenced types were genotype 4.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • Adult
  • Anemia, Sickle Cell / complications
  • Child
  • Child, Preschool
  • Female
  • Genotype
  • Hepacivirus / classification*
  • Hepacivirus / genetics*
  • Hepacivirus / isolation & purification
  • Hepatitis C / epidemiology*
  • Hepatitis C / virology*
  • Hepatitis C Antibodies / blood
  • Humans
  • Infant
  • Male
  • Molecular Sequence Data
  • Mothers*
  • Phylogeny
  • RNA, Viral / analysis
  • RNA, Viral / blood
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA
  • Transfusion Reaction
  • Uganda / epidemiology

Substances

  • Hepatitis C Antibodies
  • RNA, Viral

Associated data

  • GENBANK/AY577578
  • GENBANK/AY577579
  • GENBANK/AY577580
  • GENBANK/AY577581
  • GENBANK/AY577582
  • GENBANK/AY577583
  • GENBANK/AY577584
  • GENBANK/AY577585
  • GENBANK/AY577586