Alpha-amylase inhibitors from Brazilian seaweeds and their hypoglycemic potential

Valéria L Teixeira; Fabíola D Rocha; Peter J Houghton; Maria Auxiliadora C Kaplan; Renato C Pereira

doi:10.1016/j.fitote.2006.09.017

Alpha-amylase inhibitors from Brazilian seaweeds and their hypoglycemic potential

Fitoterapia. 2007 Jan;78(1):35-6. doi: 10.1016/j.fitote.2006.09.017. Epub 2006 Sep 23.

Authors

Valéria L Teixeira¹, Fabíola D Rocha, Peter J Houghton, Maria Auxiliadora C Kaplan, Renato C Pereira

Affiliation

¹ Departamento de Biologia Marinha, Instituto de Biologia, Universidade Federal Fluminense, PO Box 100.644, Niterói, RJ, 24001-970, Brazil. gbmvalt@bm.uff.br

PMID: 17067759
DOI: 10.1016/j.fitote.2006.09.017

Abstract

The acetone crude extract of Lobophora variegata did not show any alpha-amylase inhibition activity. On the contrary, acetone crude extract of both Spatoglossum schroederi and Caulerpa racemosa inhibited the enzyme activity, with an ED(50) of 0.58 and 0.09 mg/ml.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Brazil
Enzyme Inhibitors / administration & dosage
Enzyme Inhibitors / pharmacology*
Enzyme Inhibitors / therapeutic use
Humans
Hypoglycemic Agents / administration & dosage
Hypoglycemic Agents / pharmacology*
Hypoglycemic Agents / therapeutic use
Inhibitory Concentration 50
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use
Seaweed*
alpha-Amylases / adverse effects*

Substances

Enzyme Inhibitors
Hypoglycemic Agents
Plant Extracts
alpha-Amylases