We present the case of two women with FUO as first manifestation of a cervical carcinoma. In both cases, wide spectrum antibiotic treatment (and tuberculostatic medication in the first woman) were not useful to stop fever. Autoimmune diseases tests were normal. Just image techniques let us detect a suspicious lesion (specially, abdomino-pelvic magnetic resonance) and biopsy gave the definitive diagnosis. A radical surgery caused the fever resolution. These are two cases of cervical cancer as cause of fever of unknown origin and, at the moment, we have not found another cases in the literature. We should consider this kind of tumor as a possible origin of fever.