[Effects and comparison of seed oil and sarcocarp oil of Hippophae rhamnoides on rats with experimental hepatocirrhosis]

Zhongguo Zhong Yao Za Zhi. 2006 Jul;31(13):1100-2.
[Article in Chinese]

Abstract

Objective: A study was carried out to investigate the effects of seed oil and sarcocarp oil of Hippophae rhamnoides on rats with experimental hepatocirrhosis, and comparison between the two.

Method: A rat model of experimental hepatocirrhosis was set up by feeding CCl4. Different concentration of seed oil and sarcocarp oil of H. rhamnoides were feed to those rats for 45 d, then the changes of activity of ALT in serum and SOD in liver were measured.

Result: Both of seed oil and sarcocarp oil can control the increase of ALT in serum and the decrease of SOD evidently, and the effect of seed oil was turn out to be a little better than sarcocarp oil.

Conclusion: Seed oil was more effective than sarcocarp oil of H. rhamnoides in alleviating liver injury caused by CCl4.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Alanine Transaminase / blood
  • Animals
  • Carbon Tetrachloride Poisoning
  • Drugs, Chinese Herbal / isolation & purification
  • Drugs, Chinese Herbal / pharmacology
  • Fruit / chemistry
  • Hippophae* / chemistry
  • Liver / enzymology
  • Liver Cirrhosis, Experimental / etiology
  • Liver Cirrhosis, Experimental / metabolism*
  • Male
  • Plant Oils / isolation & purification
  • Plant Oils / pharmacology*
  • Plants, Medicinal / chemistry
  • Rats
  • Seeds / chemistry
  • Superoxide Dismutase / metabolism

Substances

  • Drugs, Chinese Herbal
  • Plant Oils
  • Superoxide Dismutase
  • Alanine Transaminase