Abstract
A case of primary carcinoid tumor of the liver with striking morphologic and electron microscopic features is reported. Conventional histologic examination showed a prominent paranuclear clear zone in numerous tumor cells. By electron microscopic examination, this clear zone corresponded to a paranuclear mass of intermediate filaments admixed with neurosecretory granules and other cytoplasmic organelles.
MeSH terms
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Aged
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Antigens, Neoplasm / analysis
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Carcinoembryonic Antigen / analysis
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Carcinoid Tumor / chemistry
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Carcinoid Tumor / immunology
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Carcinoid Tumor / pathology*
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Chromogranins / analysis
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Cytoplasmic Granules / pathology
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Humans
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Immunohistochemistry
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Keratins / analysis
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Liver Neoplasms / chemistry
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Liver Neoplasms / immunology
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Liver Neoplasms / pathology*
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Male
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Membrane Glycoproteins / analysis
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Microscopy, Electron
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Mucin-1
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Organelles / pathology
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Phosphopyruvate Hydratase / analysis
Substances
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Antigens, Neoplasm
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Carcinoembryonic Antigen
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Chromogranins
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Membrane Glycoproteins
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Mucin-1
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Keratins
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Phosphopyruvate Hydratase