Silenes in organic synthesis: a short synthesis of prelactone B

Org Biomol Chem. 2006 Sep 7;4(17):3223-4. doi: 10.1039/b608989e. Epub 2006 Jul 20.

Abstract

A sequence involving dihydroxylation and acid induced fragmentation of silene generated silacyclohexenes represents the key step in a concise synthetic route to beta-hydroxy-delta-lactones.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chemistry, Organic
  • Indicators and Reagents
  • Lactones / chemical synthesis*
  • Lactones / chemistry
  • Models, Molecular
  • Molecular Conformation
  • Organic Chemistry Phenomena
  • Stereoisomerism

Substances

  • Indicators and Reagents
  • Lactones
  • prelactone B