Increased risk of chronic suppurative lung disease after measles or pertussis in non-vaccinated children

Vaccine. 2007 Jan 5;25(3):402-3. doi: 10.1016/j.vaccine.2006.09.045. Epub 2006 Sep 27.

Abstract

We retrospectively analysed 23 children originating from Campania--Southern Italy--with recurrent pneumonia and chest high-resolution computed tomography (HRCT) proven bronchiectasis. In six patients (26%) who had not undergone measles or pertussis vaccination, recurrent pneumonia started after an episode of lower respiratory tract infection complicating pertussis (n=2) or measles (n=4), contracted at a mean age of 3.6 years. Thirty-three percent (2/6) and 67% (4/6) of the patients had bilateral or monolobar disease, respectively, while in two subjects (33%) bronchiectasis were found in all lobes. These findings indicate an increased risk of developing bronchiectasis after measles or pertussis.

Publication types

  • Comment
  • Letter

MeSH terms

  • Bronchiectasis / epidemiology
  • Bronchiectasis / etiology
  • Child
  • Chronic Disease
  • Disease Outbreaks
  • Humans
  • Italy / epidemiology
  • Lung Diseases / epidemiology
  • Lung Diseases / etiology*
  • Measles / complications*
  • Measles / epidemiology
  • Pneumonia / epidemiology
  • Pneumonia / etiology
  • Risk
  • Vaccination
  • Whooping Cough / complications*
  • Whooping Cough / epidemiology