Surface area: a better predictor of disease severity than the height and volume of the barium column in patients with primary achalasia

Eur J Gastroenterol Hepatol. 2006 Nov;18(11):1203-8. doi: 10.1097/01.meg.0000236882.36590.76.

Abstract

Objective: Subjective assessment of primary achalasia is not accurate. We aimed to study the utility of surface area of barium retention in the objective assessment of these patients.

Methods: Subjective and objective esophageal functions of 99 patients with primary achalasia were evaluated initially and 43 of them were reevaluated 1 month after balloon dilation.

Results: Before dilation: Ninety-nine patients were enrolled. Forty-one of them were male. The mean age was 37.5+/-15.3 years. The mean score, resting lower esophageal sphincter pressure, height, surface and volume of barium retention at 5 min were 8.03+/-3.1, 59.1+/-20 mmHg, 9.9+/-4.9 cm, and 23.6+/-13.9 cm and 53.2+/-47.7 cm, respectively. Surface area at 5 min had best correlation and predictive value for resting lower esophageal sphincter pressure. After dilation: Forty-three of 99 patients were reevaluated after balloon dilation. The mean age was 36.8+/-13.6 years. Seventeen of them were male. Mean score, resting lower esophageal sphincter pressure, height, surface area and volume of barium retention at 5 min dropped significantly after dilation. Surface area at 5 min had best correlation and predictive value for lower esophageal sphincter pressure.

Conclusions: Surface area of barium retention at 5 min is an accurate objective tool to assess patients with primary achalasia. It is cheap and easy to perform; therefore, it could be used more frequently in postdilation follow-up.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Barium Sulfate
  • Catheterization / methods
  • Contrast Media
  • Esophageal Achalasia / diagnostic imaging*
  • Esophageal Achalasia / pathology
  • Esophageal Achalasia / physiopathology
  • Esophagus / diagnostic imaging*
  • Esophagus / pathology
  • Esophagus / physiopathology
  • Female
  • Follow-Up Studies
  • Humans
  • Logistic Models
  • Male
  • Manometry
  • Middle Aged
  • Peristalsis
  • Radiography

Substances

  • Contrast Media
  • Barium Sulfate