Abstract
Raman spectroscopy (RS) study shows that the "potential sensor" responds to changes in intramembrane potential by conformational changes. The mechanism of regulation of the channel "gate" by the carotenoid potential sensor is discussed.
MeSH terms
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Animals
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Calcium Chloride / pharmacology
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Carotenoids / pharmacology
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Egtazic Acid / pharmacology
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In Vitro Techniques
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Ion Channels / physiology*
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Ion Channels / ultrastructure
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Lanthanum / pharmacology
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Liposomes
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Membrane Potentials / drug effects
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Potassium Chloride / pharmacology
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Ranidae
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Sciatic Nerve / physiology*
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Spectrum Analysis, Raman / methods
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Valinomycin / pharmacology
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beta Carotene
Substances
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Ion Channels
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Liposomes
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beta Carotene
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lanthanum chloride
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Valinomycin
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Carotenoids
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Egtazic Acid
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Potassium Chloride
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Lanthanum
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Calcium Chloride