Cardiac arrhythmias and atrioventricular block in a cohort of asymptomatic individuals without heart disease

Cardiology. 2007;108(2):111-6. doi: 10.1159/000095950. Epub 2006 Sep 29.

Abstract

Aims: To evaluate cardiac arrhythmias and rhythm disturbances on 24 h ambulatory electrocardiographic monitoring in a cohort of asymptomatic healthy individuals with normal clinical examination.

Methods and results: 625 asymptomatic healthy individuals, in the age range 15-83 (mean 42, SD 11.9) years; 276 (44.2%) men and 349 (55.8%) women were submitted to 24-hour ambulatory electrocardiographic monitoring. Statistical analysis was performed with likelihood ratio test and automatic backward logistic regression. The frequency of atrial arrhythmias (p < 0.0001; OR 1.059; 95% CI 1.050-1068) and of ventricular arrhythmias (p < 0.0001; OR 1.023; 95% CI 1.017-1.029) increased for each age increase of 1 year; neither atrial nor ventricular arrhythmias demonstrated a statistically significant difference relative to gender. Transient second-degree atrioventricular block (Mobitz I) was observed in 14 (2.2%) individuals and was more frequent in individuals with resting heart rate <60 bpm (p = 0.006; OR 6.7, 95% CI 1.7-25.5).

Conclusion: The frequency of atrial and ventricular arrhythmias increased with age and did not demonstrate a significant difference relative to gender. Transient atrioventricular block was more frequent in individuals with lower resting heart rate.

MeSH terms

  • Adolescent
  • Adult
  • Age Distribution
  • Aged
  • Aged, 80 and over
  • Arrhythmias, Cardiac / epidemiology*
  • Atrial Function / physiology
  • Brazil / epidemiology
  • Electrocardiography, Ambulatory
  • Female
  • Heart Block / epidemiology
  • Heart Rate / physiology
  • Humans
  • Male
  • Middle Aged
  • Ventricular Function / physiology