High-dose inhaled corticosteroid use in childhood asthma: an observational study of GP prescribing

Br J Gen Pract. 2006 Oct;56(531):788-90.

Abstract

Inhaled corticosteroids are effective and safe treatments for childhood asthma in standard doses, yet at high dosages they may be associated with adverse events and suboptimal outcomes; add-on therapy is, therefore, recommended to minimise their use. We quantified prescribing of high-dose inhaled corticosteroids and add-on therapy in children in July 2003 and found that high-dose inhaled corticosteroids were prescribed to 10% of children aged 5-11 years and 6% of under-5's who were treated for asthma. Add-on therapy was lacking for almost half of these individuals. Some children were receiving treatment not in accord with current licences and evidence-based recommendations and, as such, may be at risk of adverse outcomes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Administration, Inhalation
  • Adrenal Cortex Hormones / administration & dosage*
  • Adrenal Cortex Hormones / adverse effects
  • Anti-Asthmatic Agents / administration & dosage*
  • Anti-Asthmatic Agents / adverse effects
  • Asthma / drug therapy*
  • Child
  • Child, Preschool
  • Drug Therapy, Combination
  • Family Practice
  • Guideline Adherence*
  • Humans
  • Practice Guidelines as Topic
  • Practice Patterns, Physicians'*
  • Risk Factors

Substances

  • Adrenal Cortex Hormones
  • Anti-Asthmatic Agents