A severe case of neonatal toxic shock syndrome-like exanthematous disease with superantigen-induced high T cell response

Pediatr Infect Dis J. 2006 Oct;25(10):950-2. doi: 10.1097/01.inf.0000238144.22201.4a.

Abstract

Most newborn patients with a neonatal type of toxic shock syndrome (TSS), called neonatal TSS-like exanthematous disease (NTED), exhibit mild clinical symptoms. We present the case of a patient with NTED who exhibited exceptionally severe clinical symptoms and an adult-type T cell response to the causative toxin TSS toxin-1.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Toxins / immunology*
  • Enterotoxins / immunology*
  • Female
  • Flow Cytometry
  • Humans
  • Infant, Newborn
  • Shock, Septic / immunology*
  • Shock, Septic / microbiology
  • Staphylococcal Infections / immunology*
  • Staphylococcal Infections / microbiology
  • Staphylococcus aureus / isolation & purification
  • Superantigens / immunology*
  • T-Lymphocyte Subsets / immunology
  • T-Lymphocytes / immunology*

Substances

  • Bacterial Toxins
  • Enterotoxins
  • Superantigens
  • enterotoxin F, Staphylococcal