Granulatoside A, a starfish steroid glycoside, enhances PC12 cell neuritogenesis induced by nerve growth factor through an activation of MAP kinase

ChemMedChem. 2006 Dec;1(12):1351-4. doi: 10.1002/cmdc.200600190.

Authors

Jianhua Qi¹, Chunguang Han, Yumi Sasayama, Hiroko Nakahara, Takahiro Shibata, Koji Uchida, Makoto Ojika

Affiliation

¹ Graduate School of Bioagricultural Sciences, Nagoya University, Chikusa-ku, Nagoya 464-8601, Japan.

PMID: 17001614
DOI: 10.1002/cmdc.200600190

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cell Differentiation / drug effects
Cell Survival / drug effects
Dose-Response Relationship, Drug
Enzyme Activation / drug effects
Glycosides / chemistry
Glycosides / pharmacology*
Mitogen-Activated Protein Kinases / drug effects*
Mitogen-Activated Protein Kinases / metabolism*
Molecular Conformation
Nerve Growth Factors / pharmacology*
Neurites / drug effects*
Neurites / enzymology
Neurites / metabolism
PC12 Cells
Rats
Starfish / chemistry*
Stereoisomerism
Steroids / chemistry
Steroids / pharmacology*
Structure-Activity Relationship
Time Factors

Substances

Glycosides
Nerve Growth Factors
Steroids
granulatoside A
Mitogen-Activated Protein Kinases