Single-molecule mountains yield nanoscale cell images

Nat Methods. 2006 Oct;3(10):781-2. doi: 10.1038/nmeth1006-781.

Abstract

Methods to simultaneously localize the positions of multiple single fluorophores by precisely determining their individual positions are now yielding impressive gains in fluorescence microscopy resolution.

Publication types

  • Comment
  • News

MeSH terms

  • Cells / chemistry*
  • Cells / ultrastructure*
  • Fluorescent Dyes
  • Imaging, Three-Dimensional / methods*
  • Microscopy, Fluorescence / methods
  • Nanotechnology / methods*
  • Proteins / chemistry*
  • Sensitivity and Specificity

Substances

  • Fluorescent Dyes
  • Proteins