Abstract
A novel Escherichia coli outer membrane protein A (OmpA) was discovered through a proteomic investigation of cell surface proteins. DNA polymorphisms were localized to regions encoding the protein's surface-exposed loops which are known phage receptor sites. Bacteriophage sensitivity testing indicated an association between bacteriophage resistance and isolates having the novel ompA allele.
MeSH terms
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Alleles*
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Amino Acid Sequence
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Animals
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Australia
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Bacterial Outer Membrane Proteins / chemistry
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Bacterial Outer Membrane Proteins / genetics*
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Coliphages / physiology*
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Escherichia coli / genetics
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Escherichia coli / isolation & purification
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Escherichia coli / virology*
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Escherichia coli Proteins / chemistry
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Escherichia coli Proteins / genetics*
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Humans
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Marsupialia
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Molecular Sequence Data
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Sequence Analysis, DNA
Substances
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Bacterial Outer Membrane Proteins
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Escherichia coli Proteins
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OMPA outer membrane proteins
Associated data
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GENBANK/AY682204
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GENBANK/AY682205
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GENBANK/AY682206