Pretreatment social functioning predicts 1-year outcome in early onset psychosis

Acta Psychiatr Scand. 2006 Oct;114(4):249-56. doi: 10.1111/j.1600-0447.2006.00773.x.

Abstract

Objective: The aim was to investigate the association of pretreatment social functioning (12 months before initial presentation) with symptom dimensions and social functioning at 1-year follow-up.

Method: Fifty-six adolescents, age 14-18, first admitted for early onset psychosis, were evaluated at baseline and 1-year follow-up assessing psychopathology (PANSS), social functioning (Strauss and Carpenter Prognostic Scale), and duration of untreated psychosis (DUP).

Results: Adolescents with low pretreatment social functioning were at risk of more severe negative symptoms and lower social functioning at follow-up. Negative symptoms at baseline were less predictive and DUP was not predictive in this sample.

Conclusion: Results of this study suggest a strong longitudinal inter-relatedness between social functioning and negative symptoms in this age group. An integrative treatment approach including family interventions, social skills training, long-term specialized work/school rehabilitation, and adequate antipsychotic treatment is warranted to improve both, social functioning and negative symptoms.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Age Factors
  • Demography
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Predictive Value of Tests
  • Prospective Studies
  • Psychotic Disorders* / diagnosis
  • Psychotic Disorders* / psychology
  • Psychotic Disorders* / therapy
  • Severity of Illness Index
  • Social Behavior*
  • Surveys and Questionnaires
  • Treatment Outcome