Abstract
Highly virulent community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) with Panton-Valentine leukocidin (PVL) is common worldwide. Using antimicrobial drug susceptibility testing, staphylococcal cassette chromosome mec typing, exotoxin profiling, and pulsed-field gel electrophoresis typing, we provide evidence that supports the relationship between nasal strains of PVL-positive MRSA and community-acquired disease.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Anti-Bacterial Agents / pharmacology
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Bacterial Toxins / genetics
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Bacterial Toxins / metabolism*
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Bacterial Typing Techniques
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Child
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Child, Preschool
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Community-Acquired Infections / epidemiology*
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Community-Acquired Infections / microbiology
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Exotoxins / genetics
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Exotoxins / metabolism*
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Humans
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Leukocidins
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Methicillin Resistance*
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Microbial Sensitivity Tests
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Nasal Cavity / microbiology
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Prevalence
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Staphylococcal Infections / epidemiology*
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Staphylococcal Infections / microbiology
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Staphylococcus aureus / classification
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Staphylococcus aureus / drug effects*
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Staphylococcus aureus / genetics
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Taiwan / epidemiology
Substances
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Anti-Bacterial Agents
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Bacterial Toxins
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Exotoxins
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Leukocidins
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Panton-Valentine leukocidin