Abstract
The present study shows the evaluation of clinical state and serum level of tricyclic antidepressants in thirty-eight depressive younger and elderly patients during 8-week observation. We observed no statistically significant differences, neither in psychometric scale scores nor in drug serum levels in both groups of patients.
Publication types
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Clinical Trial
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Comparative Study
MeSH terms
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Adult
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Age Factors
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Aged
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Aging*
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Antidepressive Agents, Tricyclic / adverse effects
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Antidepressive Agents, Tricyclic / blood
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Antidepressive Agents, Tricyclic / pharmacokinetics
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Antidepressive Agents, Tricyclic / therapeutic use*
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Clomipramine / therapeutic use
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Depression / blood
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Depression / drug therapy*
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Drug Monitoring*
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Female
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Humans
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Imipramine / therapeutic use
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Male
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Middle Aged
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Psychiatric Status Rating Scales
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Time Factors
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Treatment Outcome
Substances
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Antidepressive Agents, Tricyclic
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Clomipramine
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Imipramine