Synthesis of platinum(II) chiral tetraamine coordination complexes

Adel Nefzi; Cornelia E Hoesl; Clemencia Pinilla; George B Kauffman; Gerald M Maggiora; Elena Pasquale; Richard A Houghten

doi:10.1021/cc060045h

Synthesis of platinum(II) chiral tetraamine coordination complexes

J Comb Chem. 2006 Sep-Oct;8(5):780-3. doi: 10.1021/cc060045h.

Authors

Adel Nefzi¹, Cornelia E Hoesl, Clemencia Pinilla, George B Kauffman, Gerald M Maggiora, Elena Pasquale, Richard A Houghten

Affiliation

¹ Torrey Pines Institute for Molecular Studies, 3550 General Atomics Court, San Diego, California 92121, USA.

PMID: 16961414
DOI: 10.1021/cc060045h

Abstract

The individual and combinatorial syntheses of individual as well as a mixture-based diversity of 195 112 platinum(II) coordination complexes of chiral tetraamines are described. The use of both solid-phase synthesis and solution phase follow-on approaches were found to best afford the title compounds.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Combinatorial Chemistry Techniques*
Nitrogen Compounds / chemical synthesis
Nitrogen Compounds / chemistry*
Platinum Compounds / chemical synthesis
Platinum Compounds / chemistry*
Solutions / chemistry
Stereoisomerism

Substances

Nitrogen Compounds
Platinum Compounds
Solutions
tetraammineplatinum(II)

Abstract

Publication types

MeSH terms

Substances

Grants and funding