Abstract
The protective effects of red potato extract (RPE) as to liver damage were determined in D-galactosamine (GalN)-intoxicated rats. Increases in serum aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase activities, all of which were induced by GalN injection, decreased in RPE administered rats, suggesting that RPE acts as a functional food showing anti-hepatotoxicity.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Alanine Transaminase / blood
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Animals
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Anthocyanins / isolation & purification
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Anthocyanins / pharmacology*
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Antioxidants / isolation & purification
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Antioxidants / pharmacology*
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Aspartate Aminotransferases / blood
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Chemical and Drug Induced Liver Injury*
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Galactosamine / metabolism
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Galactosamine / toxicity
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Glutathione / metabolism
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L-Lactate Dehydrogenase / blood
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Liver Diseases / prevention & control*
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Male
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Plant Extracts / pharmacology*
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Random Allocation
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Rats
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Rats, Inbred F344
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Solanum tuberosum / chemistry*
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Thiobarbituric Acid Reactive Substances / metabolism
Substances
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Anthocyanins
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Antioxidants
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Plant Extracts
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Thiobarbituric Acid Reactive Substances
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Galactosamine
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L-Lactate Dehydrogenase
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Aspartate Aminotransferases
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Alanine Transaminase
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Glutathione