Chemical technologies for probing glycans

Cell. 2006 Sep 8;126(5):851-4. doi: 10.1016/j.cell.2006.08.017.

Abstract

Glycans are central to many biological processes, but efforts to define their functions at the molecular level have been frustrated by a lack of suitable technologies. Here we highlight chemical tools that are beginning to address this need.

Publication types

  • Review

MeSH terms

  • Carbohydrate Conformation
  • Carbohydrate Sequence
  • Enzyme Inhibitors / pharmacology
  • Glycoproteins / chemistry*
  • Glycoproteins / metabolism
  • Glycosylation
  • Glycosyltransferases / antagonists & inhibitors
  • Glycosyltransferases / metabolism
  • Green Fluorescent Proteins
  • Molecular Sequence Data
  • Photoaffinity Labels
  • Protein Array Analysis*
  • Protein Conformation
  • Protein Processing, Post-Translational* / drug effects
  • Proteomics*
  • Tunicamycin / pharmacology

Substances

  • Enzyme Inhibitors
  • Glycoproteins
  • Photoaffinity Labels
  • Tunicamycin
  • Green Fluorescent Proteins
  • Glycosyltransferases