Abstract
Nanocompatible chemistry which utilizes a novel nontoxic phosphino amino acid as a reducing agent has resulted in the development of therapeutically useful gold nanoparticles under biologically benign media. Stabilization of gold nanoparticles by the edible gum arabic matrix has provided an effective pathway toward in vivo stable target-specific gold nanoparticles.
Publication types
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Research Support, N.I.H., Extramural
MeSH terms
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Animals
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Biocompatible Materials / chemistry*
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Biocompatible Materials / pharmacokinetics
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Drug Stability
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Gold / chemistry*
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Gold / pharmacokinetics
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Metal Nanoparticles / chemistry*
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Mice
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Mice, Inbred Strains
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Microscopy, Electron, Transmission
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Nanomedicine*
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Particle Size
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Surface Properties
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Tissue Distribution
Substances
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Biocompatible Materials
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Gold