Nasal airway dimensions of adults with cleft lip and palate: differences among cleft types

Cleft Palate Craniofac J. 2005 Jul;42(4):396-402. doi: 10.1597/03-081.1.

Abstract

Objective: To determine the nasal airway dimensions in adults with repaired cleft lip and palate by rhinomanometry and to analyze the reduction associated with different types of clefts.

Model: A prospective analysis comparing three types of previously repaired clefts: bilateral cleft lip and palate (BCLP), unilateral cleft lip and palate (UCLP), and isolated cleft palate (CP) at the 5% level of significance.

Setting: Laboratory of Physiology, Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo, Bauru, Brazil.

Participants: Fifty-three subjects aged 18 to 35 years (17 BCLP, 16 UCLP, 20 CP) and a group of 20 individuals without cleft (N).

Variables: Minimum cross-sectional nasal area assessed by posterior (PR) and anterior (AR) rhinomanometry and nasopharyngeal area assessed by modified AR.

Results: Mean (+/- 1 SD) nasal areas obtained by PR were: 0.47 +/- 0.16 cm(2) (BCLP), 0.57 +/- 0.19 cm(2) (UCLP), 0.61 +/- 0.13 cm(2) (CP), and 0.60 +/- 0.10 cm(2) (N). The mean value for the BCLP group was significantly smaller than that for the N and CP groups. The remaining values did not differ from one another. The proportion of subjects with subnormal areas obtained by PR was 41%, 19%, and 0% for groups BCLP, UCLP, and CP, respectively. Similar results were obtained by AR. All subjects presented a nasopharyngeal area larger than 0.80 cm(2), denoting absence of obstruction in the nasopharynx.

Conclusions: In adulthood BCLP is the type of cleft associated with a greater reduction of nasal airway, compared with UCLP and CP, suggesting that adults with BCLP are at a greater risk for nasal obstruction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Airway Obstruction / diagnosis
  • Airway Obstruction / etiology
  • Anatomy, Cross-Sectional
  • Cleft Lip / classification*
  • Cleft Lip / complications
  • Cleft Lip / pathology*
  • Cleft Palate / classification*
  • Cleft Palate / complications
  • Cleft Palate / pathology*
  • Female
  • Humans
  • Male
  • Nasal Cavity / anatomy & histology
  • Nasal Cavity / pathology*
  • Nasopharynx / anatomy & histology
  • Nasopharynx / pathology*
  • Prospective Studies
  • Reference Values
  • Rhinomanometry