Herpes zoster ophthalmicus in otherwise healthy children

Am J Ophthalmol. 2006 Sep;142(3):393-9. doi: 10.1016/j.ajo.2006.03.059.

Abstract

Purpose: To evaluate the complications of herpes zoster ophthalmicus (HZO) in children.

Design: Prospective-observational case series.

Methods: Ten healthy patients (five boys, five girls) with HZO were prospectively followed. Data regarding best-corrected visual acuity, biomicroscopy, intraocular pressure, corneal sensitivity, and funduscopy were collected. The median duration of follow-up was 19 months (range eight to 78 months).

Results: The mean age at presentation was 8.7 years (range two to 14 years +/-3.95). At last visit, two patients (20%) had decreased visual acuity and nine (90%) had some degree of abnormal corneal sensitivity and corneal opacity despite good final visual acuity.

Conclusion: In general, HZO seems to have a good prognosis in healthy children; nonetheless, some cases can present severe eye complications causing visual loss.

MeSH terms

  • Acyclovir / therapeutic use
  • Administration, Oral
  • Adolescent
  • Antiviral Agents / therapeutic use
  • Child
  • Child, Preschool
  • Cornea / physiology
  • Female
  • Follow-Up Studies
  • Herpes Zoster Ophthalmicus / complications*
  • Herpes Zoster Ophthalmicus / diagnosis
  • Herpes Zoster Ophthalmicus / drug therapy
  • Humans
  • Infusions, Intravenous
  • Intraocular Pressure
  • Male
  • Prognosis
  • Prospective Studies
  • Visual Acuity

Substances

  • Antiviral Agents
  • Acyclovir