Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia

Br J Clin Pharmacol. 2006 Sep;62(3):369-71. doi: 10.1111/j.1365-2125.2006.02666.x.

Abstract

Aims: To investigate the effect of menthol on swallowing reflex sensitivity in elderly patients with dysphagia.

Methods and results: The swallowing reflex sensitivity of institutionalized elderly patients was evaluated as a latent time of swallowing reflex (LTSR), induced by the injection of 1 ml solution into the pharynx. LTSR was significantly shortened in a concentration-dependent manner, from 13.8 s [95% confidence interval (CI) 11.1, 16.5] by distilled water to 9.4 s (95% CI 7.1. 11.8) by 10(-2)m menthol.

Conclusion: Using menthol with elderly patients with dysphagia may improve the sensitivity of their swallowing reflex, resulting in prevention of aspiration pneumonia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged, 80 and over
  • Deglutition Disorders / drug therapy*
  • Humans
  • Injections
  • Menthol / administration & dosage*
  • Pneumonia, Aspiration / prevention & control*
  • Reflex

Substances

  • Menthol