Effect of transplantation of cultured human neural stem and progenitor cells on regeneration of the cornea after chemical burn

Bull Exp Biol Med. 2006 Jan;141(1):129-32. doi: 10.1007/s10517-006-0112-5.

Abstract

We studied the effect of cultured human fetal (8-12 weeks gestation) neural stem and progenitor cells on regeneration of rabbit cornea after alkaline burn. A single subconjunctival injection of cell culture suspension after burn injury significantly accelerated regeneration of the anterior and posterior epithelium in comparison with the control group.

MeSH terms

  • Alkalies / toxicity
  • Animals
  • Cornea / pathology
  • Cornea / physiology*
  • Corneal Diseases / pathology
  • Corneal Diseases / therapy*
  • Eye Burns / chemically induced
  • Eye Burns / pathology
  • Eye Burns / therapy*
  • Fetal Tissue Transplantation
  • Humans
  • Neurons / cytology
  • Neurons / transplantation*
  • Rabbits
  • Regeneration*
  • Stem Cell Transplantation*

Substances

  • Alkalies