Marked abnormal quadruple screen in a patient with severe preeclampsia at 20 weeks with a triploid fetus

J Matern Fetal Neonatal Med. 2006 Jul;19(7):443-4. doi: 10.1080/14767050600553084.

Abstract

Severe preeclampsia rarely occurs prior to 20 weeks of gestation except in pregnancies with triploidy. The patient reported herein is a 29-year-old primigravida who developed severe preeclampsia at 20 weeks of gestation. Evaluation of the pregnancy demonstrated a markedly abnormal quadruple screen. Amniocentesis demonstrated a fetus with triploidy, despite a normal appearance.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amniocentesis
  • Chorionic Gonadotropin / blood
  • Chromosome Aberrations / embryology*
  • Female
  • Fetal Death
  • Fetal Diseases / diagnosis*
  • Fetal Diseases / genetics
  • Gestational Age
  • Humans
  • Inhibins / blood
  • Polyploidy*
  • Pre-Eclampsia / etiology*
  • Pregnancy
  • alpha-Fetoproteins / analysis

Substances

  • Chorionic Gonadotropin
  • alpha-Fetoproteins
  • inhibin A
  • Inhibins