Transcatheter cryotherapy for the treatment of supraventricular tachyarrhythmias in children: a single center experience

J Interv Card Electrophysiol. 2006 Apr;15(3):191-6. doi: 10.1007/s10840-006-9012-x. Epub 2006 Aug 17.

Abstract

Introduction: Transcatheter cryotherapy is an emerging technology for the treatment of children with supraventricular tachyarrhythmias. Limited data exist regarding the use of cryoablation therapy in children. We report a single center's experience with transcatheter cryoablation in the pediatric population.

Methods and results: A retrospective review of demographic, procedural and outcome data was performed for patients undergoing cryoablation for treatment of supraventricular tachycardia (SVT). A historical control group was taken from the 3 years preceding the introduction of cryoablation. Between August 2003 and November 2005, 83 cryoablation procedures were performed in 81 patients (age: 4 to 21 years, mean: 13.4 years) for AV nodal reentrant tachycardia (AVNRT--53), AV reentrant tachycardia (AVRT--20), ectopic atrial tachycardia (EAT--9), and junctional ectopic tachycardia (JET--1). The acute success rate for all procedures was 88% (AVNRT: 96%, AVRT: 85%, EAT: 55%, and JET: 100%). Of 72 patients that underwent successful cryoablation, nine experienced recurrence of SVT (12.5%). The control group consisted of 73 patients (AVNRT--60, AVRT--13). There were no differences in demographic data between the two groups. The overall success rate for the RFA group (96%) was identical to that for patients with AVNRT and AVRT undergoing cryoablation. The recurrence rate for RFA (10%) was less but not significantly different than that for cryoablation (12%). There were no complications in either group.

Conclusions: Cryoablation is a safe and effective alternative for the treatment of SVT in children.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial

MeSH terms

  • Adolescent
  • Adult
  • Cardiac Catheterization / methods*
  • Catheter Ablation*
  • Child
  • Child, Preschool
  • Cryotherapy / methods*
  • Female
  • Humans
  • Male
  • Tachycardia, Supraventricular / therapy*
  • Treatment Outcome