FDG positron emission tomography/computerized tomography features of bleomycin-induced pneumonitis

J Thorac Imaging. 2006 Aug;21(3):228-30. doi: 10.1097/01.rti.0000209821.43379.8a.

Abstract

Bleomycin is a widely used chemotherapeutic that has been shown to induce life-threatening interstitial lung disease in a small subset of patients. We report a case of bleomycin-induced pneumonitis in a patient treated for Hodgkin lymphoma with severe clinical respiratory symptoms, a marked restrictive pattern on pulmonary function tests, and FDG avid lymphadenopathy and diffuse increased uptake involving both lungs on imaging. To our knowledge, the in-line computed tomography/18F-fluorodeoxyglucose positron emission tomography of bleomycin induced pneumonitis has not been previously reported in the literature.

Publication types

  • Case Reports

MeSH terms

  • Antibiotics, Antineoplastic / adverse effects*
  • Bleomycin / adverse effects*
  • Diagnosis, Differential
  • Female
  • Fluorodeoxyglucose F18*
  • Hodgkin Disease / diagnosis
  • Hodgkin Disease / drug therapy*
  • Humans
  • Lymphatic Diseases / complications
  • Lymphatic Diseases / diagnosis
  • Lymphatic Diseases / diagnostic imaging
  • Middle Aged
  • Pneumonia / chemically induced*
  • Pneumonia / complications
  • Pneumonia / diagnosis*
  • Positron-Emission Tomography
  • Radiopharmaceuticals
  • Tomography, X-Ray Computed

Substances

  • Antibiotics, Antineoplastic
  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18
  • Bleomycin