Abstract
Oral administration of hexanes, chloroform, and ethyl acetate extracts of the leaves of Hyptis pectinata significantly reduced the number of writhing induced by acetic acid and increased the response to thermal stimuli in hot-plate test. Such effect was completely reversed by the opioid antagonist naloxone.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Acetic Acid
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Analgesics / administration & dosage
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Analgesics / pharmacology*
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Analgesics / therapeutic use
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Animals
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Dose-Response Relationship, Drug
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Female
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Hot Temperature
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Hyptis*
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Male
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Mice
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Pain / chemically induced
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Pain / prevention & control*
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Pain Measurement / drug effects
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Phytotherapy*
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Plant Extracts / administration & dosage
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Plant Extracts / pharmacology*
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Plant Extracts / therapeutic use
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Plant Leaves
Substances
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Analgesics
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Plant Extracts
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Acetic Acid