The present study explored variations in online communication and relationship preferences for friends, family, coworkers, and unknown individuals across gender (men, women), age (young, middle, late), and duration of Internet use (low, medium, high). A total of 174 individuals participated in this study. They were divided into two gender (86 men and 88 women), three age (60 young, 60 middle, and 54 late) and three Internet use duration (60 low, 58 medium, and 54 high) groups. All participants completed several questionnaires that assessed online communication and relationship building preferences. Results indicated no significant main effect for gender and online communication and relationship preferences. The main effect for age was significant for online communication with friends and unknown individuals. Young adults indicated their higher preferences for online communication with friends and unknown individuals compared to middle and late adult age groups. The main effect for duration of Internet use was significant for online communication and relationship preferences. High Internet users indicated higher scores on online communication and relationship building, compared to their counterparts. No significant main effects for duration of Internet use were significant on any of the offline characteristics. Implications of these findings and their relevance to mental health issues and organizational environment were discussed.