The aim of this study was to analyse, taking into consideration the infection risk factors, the incidence of fungal infections occurrence in Medical Intensive Care Units. Yeast-like fungi strains isolated from various clinical materials underwent mycological examination. Mycological diagnosis was performed in compliance with compulsory laboratory methods. The detailed observation concerned patients who were admitted to the intensive care unit by urgent reasons or because of basic disease aggravation, trauma, surgical operations and those with diabetes mellitus. The main etiological fungal infections factor were C. albicans strains. The increased incidence of C. glabrata and C. parapsilosis participation in yeast-like fungi infection pathogenesis was observed. The results presented in this study confirm, that intensive care units patients, for the reason of fungal infections, make the increased risk group.