Skeletal diversity construction via a branching synthetic strategy

Chem Commun (Camb). 2006 Aug 21:(31):3296-8. doi: 10.1039/b607710b. Epub 2006 Jul 10.

Abstract

A branching synthetic strategy was used to efficiently generate structurally diverse scaffolds, which span a broad area of chemical descriptor space, and their biological activity against MRSA was demonstrated.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis*
  • Anti-Bacterial Agents / pharmacology
  • Methicillin Resistance
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Bacterial Agents