Metabolic syndrome and gender differences in postprandial lipaemia

Eur J Cardiovasc Prev Rehabil. 2006 Aug;13(4):661-4. doi: 10.1097/01.hjr.0000224490.10845.26.

Abstract

Background: Postprandial hyperlipidaemia may be a predictor of vascular risk.

Design: We evaluated postprandial lipaemia after an oral fat tolerance test (OFTT) in men (n=41) and women (n=21) with metabolic syndrome (MetS).

Methods: Triglyceride (TG) levels were measured before and 2, 4, 6 and 8 h after the fat load.

Results: Men showed a greater plasma TG response 8 h after the fat load (284+/-117 versus 224+/-126 mg/dl, P=0.029). Only fasting TG levels significantly predicted the TG area under the curve (AUC) and incremental AUC.

Conclusions: Men had a more pronounced postprandial hypertriglyceridaemia and seem to have delayed TG clearance.

MeSH terms

  • Coronary Disease / blood
  • Coronary Disease / epidemiology
  • Coronary Disease / etiology*
  • Female
  • Follow-Up Studies
  • Greece / epidemiology
  • Humans
  • Hyperlipidemias / blood
  • Hyperlipidemias / complications*
  • Male
  • Metabolic Syndrome / blood
  • Metabolic Syndrome / complications*
  • Middle Aged
  • Postprandial Period / physiology*
  • Prevalence
  • Risk Factors
  • Sex Distribution
  • Sex Factors
  • Time Factors
  • Triglycerides / blood*

Substances

  • Triglycerides