Heteroyohimbinoid type oxindole alkaloids from Mitragyna parvifolia

Richa Pandey; Subhash C Singh; Madan M Gupta

doi:10.1016/j.phytochem.2006.06.017

Heteroyohimbinoid type oxindole alkaloids from Mitragyna parvifolia

Phytochemistry. 2006 Oct;67(19):2164-9. doi: 10.1016/j.phytochem.2006.06.017. Epub 2006 Jul 26.

Authors

Richa Pandey¹, Subhash C Singh, Madan M Gupta

Affiliation

¹ Central Institute of Medicinal and Aromatic Plants, Analytical Chemistry Division Lucknow, Uttar Pradesh 226015, India.

PMID: 16872649
DOI: 10.1016/j.phytochem.2006.06.017

Abstract

The leaves of the plant Mitragyna parvifolia have afforded two alkaloids, 16,17-dihydro-17beta-hydroxy isomitraphylline (1) and 16, 17-dihydro-17beta-hydroxy mitraphylline (2), together with two known alkaloids, isomitraphylline (3) and mitraphylline (4). The structures of 1 and 2 were elucidated using 1D and 2D NMR spectral methods, including (1)H-(1)HCOSY, DEPT, HSQC, and HMBC. Mitraphylline was the main alkaloid constituent.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Indole Alkaloids / chemistry*
Indole Alkaloids / isolation & purification
Magnetic Resonance Spectroscopy / methods
Mitragyna / chemistry*
Molecular Structure
Oxindoles
Plant Leaves / chemistry

Substances

16, 17-dihydro-17beta-hydroxy mitraphylline
16,17-dihydro-17beta-hydroxy isomitraphylline
Indole Alkaloids
Oxindoles
mitraphylline
isomitraphylline