Neovibsanin F and its congeners, rearranged vibsane-type diterpenes from Viburnum suspensum

J Nat Prod. 2006 Jul;69(7):1098-100. doi: 10.1021/np068005i.

Abstract

Three new rearranged vibsane-type diterpenes, neovibsanin F (1), 14-epi-neovibsanin F (2), and 14-epi-18-oxoneovibsanin F (3), have been isolated from the leaves of Viburnum suspensum, and their structures were elucidated on the basis of spectroscopic data and comparison with those of previously reported vibsane-type diterpenes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antineoplastic Agents, Phytogenic* / chemistry
  • Antineoplastic Agents, Phytogenic* / classification
  • Antineoplastic Agents, Phytogenic* / isolation & purification
  • Antineoplastic Agents, Phytogenic* / pharmacology
  • Artemia / drug effects
  • Diterpenes* / chemistry
  • Diterpenes* / classification
  • Diterpenes* / isolation & purification
  • Diterpenes* / pharmacology
  • Drug Screening Assays, Antitumor
  • Humans
  • KB Cells
  • Molecular Structure
  • Plant Leaves / chemistry
  • Plants, Medicinal / chemistry*
  • Viburnum / chemistry*

Substances

  • Antineoplastic Agents, Phytogenic
  • Diterpenes
  • neovibsanin F