Design and synthesis of 12-aza-epothilones (azathilones)--"non-natural" natural products with potent anticancer activity

Angew Chem Int Ed Engl. 2006 Sep 4;45(35):5880-5. doi: 10.1002/anie.200601359.
No abstract available

MeSH terms

  • Antineoplastic Agents / chemical synthesis*
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology*
  • Biological Products / chemical synthesis*
  • Biological Products / chemistry
  • Biological Products / pharmacology*
  • Cell Line, Tumor
  • Cell Proliferation
  • Chromatography, High Pressure Liquid
  • Epothilones / chemical synthesis*
  • Epothilones / chemistry
  • Epothilones / pharmacology*
  • Humans
  • Microscopy, Electron

Substances

  • Antineoplastic Agents
  • Biological Products
  • Epothilones