Inhibitory effects of selected Thai medicinal plants on Na+,K+-ATPase

Nattaya Ngamrojanavanich; Srinual Manakit; Surachai Pornpakakul; Amorn Petsom

doi:10.1016/j.fitote.2006.06.003

Inhibitory effects of selected Thai medicinal plants on Na+,K+-ATPase

Fitoterapia. 2006 Sep;77(6):481-3. doi: 10.1016/j.fitote.2006.06.003. Epub 2006 Jul 6.

Authors

Nattaya Ngamrojanavanich¹, Srinual Manakit, Surachai Pornpakakul, Amorn Petsom

Affiliation

¹ Department of Chemistry, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand. nnattaya@chula.ac.th

PMID: 16860494
DOI: 10.1016/j.fitote.2006.06.003

Abstract

Extracts of ten Thai indigenous medicinal plants having ethnomedical application in the treatment of dysuria were tested for their Na(+),K(+)-ATPase inhibitory activity. The hexane extracts of Cyperus rotundus and Orthosiphon aristatus showed high potent inhibitory activity on crude enzyme Na(+),K(+)-ATPase from rat brain.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Brain / enzymology*
Cyperus
Diuretics / administration & dosage
Diuretics / pharmacology*
Diuretics / therapeutic use
Medicine, Traditional
Orthosiphon
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use
Plants, Medicinal*
Rats
Sodium-Potassium-Exchanging ATPase / metabolism*
Thailand

Substances

Diuretics
Plant Extracts
Sodium-Potassium-Exchanging ATPase