Efficient conversion of nitronate into nitrile oxide using cyanuric chloride. One-pot synthesis of bicyclic isoxazolines and isoxazoles from nitroalkenes

Shijay Gao; Zhijay Tu; Chun-Wei Kuo; Ju-Tsung Liu; Cheng-Ming Chu; Ching-Fa Yao

doi:10.1039/b606717d

Efficient conversion of nitronate into nitrile oxide using cyanuric chloride. One-pot synthesis of bicyclic isoxazolines and isoxazoles from nitroalkenes

Org Biomol Chem. 2006 Aug 7;4(15):2851-7. doi: 10.1039/b606717d. Epub 2006 Jun 28.

Authors

Shijay Gao¹, Zhijay Tu, Chun-Wei Kuo, Ju-Tsung Liu, Cheng-Ming Chu, Ching-Fa Yao

Affiliation

¹ Department of Chemistry, National Taiwan Normal University 88, Taipei, ROC.

PMID: 16855732
DOI: 10.1039/b606717d

Abstract

Bicyclic isoxazolines and isoxazoles are obtained in good yields by proceeding through a convenient one-pot, two-step procedure utilizing 2,4,6-trichloro-1,3,5-triazine (TCT) as a dehydrating agent.