Phytochemical studies and antibacterial activity of Centaurium pulchellum Druce

Nat Prod Res. 2006 Aug;20(10):896-901. doi: 10.1080/14786410500162047.

Abstract

Two isocoumarin derivatives, one new, erythricin (1) and a known erythrocentaurin (2) were isolated from the whole plant of Centaurium pulchellum Druce. The 13C-NMR data of compound 2 are described. The structures of compounds 1, 2 were elucidated on the basis of spectral analysis including 2D-NMR experiments. Antibacterial and brine shrimp lethality assays are also described on the fractions of the plant extract.

MeSH terms

  • Animals
  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Artemia / drug effects
  • Bacteria / drug effects
  • Centaurium / chemistry*
  • Isocoumarins / chemistry
  • Isocoumarins / isolation & purification*
  • Isocoumarins / pharmacology*
  • Mass Spectrometry
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Extracts / chemistry
  • Plant Extracts / pharmacology
  • Spectrophotometry, Infrared
  • Spectrophotometry, Ultraviolet
  • Stereoisomerism

Substances

  • Anti-Bacterial Agents
  • Isocoumarins
  • Plant Extracts