Abstract
Two isocoumarin derivatives, one new, erythricin (1) and a known erythrocentaurin (2) were isolated from the whole plant of Centaurium pulchellum Druce. The 13C-NMR data of compound 2 are described. The structures of compounds 1, 2 were elucidated on the basis of spectral analysis including 2D-NMR experiments. Antibacterial and brine shrimp lethality assays are also described on the fractions of the plant extract.
MeSH terms
-
Animals
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / isolation & purification*
-
Anti-Bacterial Agents / pharmacology
-
Artemia / drug effects
-
Bacteria / drug effects
-
Centaurium / chemistry*
-
Isocoumarins / chemistry
-
Isocoumarins / isolation & purification*
-
Isocoumarins / pharmacology*
-
Mass Spectrometry
-
Microbial Sensitivity Tests
-
Molecular Structure
-
Nuclear Magnetic Resonance, Biomolecular
-
Plant Extracts / chemistry
-
Plant Extracts / pharmacology
-
Spectrophotometry, Infrared
-
Spectrophotometry, Ultraviolet
-
Stereoisomerism
Substances
-
Anti-Bacterial Agents
-
Isocoumarins
-
Plant Extracts