Functionalization of solid surfaces with thermoresponsive protein-resistant films

D O H Teare; D C Barwick; W C E Schofield; R P Garrod; A Beeby; J P S Badyal

doi:10.1021/jp052869f

Functionalization of solid surfaces with thermoresponsive protein-resistant films

J Phys Chem B. 2005 Dec 1;109(47):22407-12. doi: 10.1021/jp052869f.

Authors

D O H Teare¹, D C Barwick, W C E Schofield, R P Garrod, A Beeby, J P S Badyal

Affiliation

¹ Department of Chemistry, Science Laboratories, Durham University, Durham DH1 3LE, England, UK.

PMID: 16853918
DOI: 10.1021/jp052869f

Abstract

Pulsed plasma polymerization of N-isopropylacrylamide leads to the deposition of thermoresponsive films. The reversible (switching) behavior of these poly(N-isopropylacrylamide) surfaces has been exemplified by screening the adsorption of fibrinogen and fluorescein isothiocyanate labeled bovine serum albumin proteins by surface plasmon resonance (SPR) and fluorescence microscopy at low and elevated temperatures.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acrylic Resins / chemical synthesis
Acrylic Resins / chemistry*
Adsorption
Animals
Membranes, Artificial*
Serum Albumin, Bovine / chemistry*
Surface Properties
Temperature*

Substances

Acrylic Resins
Membranes, Artificial
poly-N-isopropylacrylamide
Serum Albumin, Bovine