A new Ru-catalyzed cascade reaction forming polycyclic cyclohexadienes from 1,6-diynes and alkenes

Jesús A Varela; Silvia G Rubín; Carlos Gonzalez-Rodríguez; Luis Castedo; Carlos Saa

doi:10.1021/ja057306w

A new Ru-catalyzed cascade reaction forming polycyclic cyclohexadienes from 1,6-diynes and alkenes

J Am Chem Soc. 2006 Jul 26;128(29):9262-3. doi: 10.1021/ja057306w.

Authors

Jesús A Varela¹, Silvia G Rubín, Carlos Gonzalez-Rodríguez, Luis Castedo, Carlos Saa

Affiliation

¹ Departamento de Química Organica y Unidad Asociada al CSIC, Facultad de Química, Universidad de Santiago de Compostela, 15782 Santiago de Compostela, Spain.

PMID: 16848424
DOI: 10.1021/ja057306w

Abstract

Functionalized bicyclic 1,3-cyclohexadienes can be easily prepared by a new cascade reaction which involves the Ru-catalyzed addition of acyclic alkenes to 1,6-diynes to give (Z)-hexatrienes, followed by a pure thermal 6e-pi electrocyclization.