Fusion and endocytosis of anionic liposomes with Ehrlich ascitic carcinoma cells

Bull Exp Biol Med. 2005 Dec;140(6):733-5. doi: 10.1007/s10517-006-0069-4.

Abstract

Polyethylene glycol 300 and low pH of the incubation medium initiate fusion of anionic lipid liposome membranes with Ehrlich ascitic carcinoma cell membranes. Some liposomes are endocytosed in cells and are distributed near the inner surface of the membrane. Liposome membranes spontaneously fuse with the cells under certain conditions.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biochemistry / methods
  • Carcinoma, Ehrlich Tumor / pathology*
  • Cell Membrane / metabolism
  • Endocytosis
  • Hydrogen-Ion Concentration
  • Liposomes / chemistry*
  • Membrane Fusion*
  • Mice
  • Phosphatidylethanolamines / chemistry
  • Polyethylene Glycols / chemistry
  • Time Factors

Substances

  • Liposomes
  • Phosphatidylethanolamines
  • Polyethylene Glycols